Let KAYAK do the searching
Based on KAYAK hotel searches, the most popular destination is Cologne (42% of total searches to Rhine). The next most popular destinations are Strasbourg (24%) and Düsseldorf (20%). Searches for hotels in Basel (15%) are also popular.
KAYAK users have found double rooms in Rhine for as cheap as $42 (Strasbourg) in the last 3 days. The average price is $338.