Let KAYAK do the searching
Based on KAYAK hotel searches, the most popular destination is Ragusa (50% of total searches to Sicily South Coast). The next most popular destinations are Marsala (25%) and Sciacca (19%). Searches for hotels in Mazara del Vallo (6%) are also popular.
KAYAK users have found double rooms in Sicily South Coast for as cheap as $57 (Caltanissetta) in the last 3 days. The average price is $227.