Let KAYAK do the searching
Based on KAYAK hotel searches, the most popular destination is Koblenz (31% of total searches to Rhineland-Palatinate). The next most popular destinations are Mainz (27%) and Trier (27%). Searches for hotels in Lieser (15%) are also popular.
KAYAK users have found double rooms in Rhineland-Palatinate for as cheap as $72 (Cochem) in the last 3 days. The average price is $247.